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Alternate Test Names:
MDS Panel test
Acute Myelogenous Leukemia Panel test
This FISH probe set detects deletion of 7q31 and monosomy 7, which are chromosomal abnormalities seen in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This FISH test is frequently utilized in the workup of MDS, which is a heterogeneous group of clonal myeloid stem cell disorders. Deletion of 7q31 is associated with an intermediate prognosis while monosomy 7 is associated with a poor prognosis.
Probe type: Dual color enumeration
CPT Code(s): 88374 (reference only; CPTs may vary)
Turnaround Time: Within 3-4 business days of receipt
Schedule: Monday - Friday
• Peripheral blood, Preferred: 3 ml in sodium heparin (green top) / Acceptable: 3 ml in EDTA (purple top) - OR -
• Bone marrow aspirate, Preferred: 1-2 ml in sodium heparin (green top) / Acceptable: 1-2 ml in EDTA (purple top) - OR -
• Fresh tissue in RPMI