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ALK protein (p80) pin


ALK protein (p80)

Methodology: IHC

Clinical Significance:
Identifies anaplastic large cell lymphoma and other T cell lymphomas. ALK is a protein overexpressed as a consequence of the (2;5) translocation that is found in anaplastic large cell lymphoma (ALCL). Expression of ALK is also seen in embryonal carcinomas and in a subset of inflammatory myofibroblastic tumors. Subcellular Localization:  Nuclear and cytoplasmic


Disease State: Large Cell Undifferentiated Malignant Neoplams

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm