ALK protein (p80) pin

IHC

ALK protein (p80)

Methodology: IHC

Clinical Significance:
Identifies anaplastic large cell lymphoma and other T cell lymphomas. ALK is a protein overexpressed as a consequence of the (2;5) translocation that is found in anaplastic large cell lymphoma (ALCL). Expression of ALK is also seen in embryonal carcinomas and in a subset of inflammatory myofibroblastic tumors.

Subcellular Localization: Nuclear and cytoplasmic

Organ:

Disease State: Anaplastic Large Cell Lymphoma (Systemic or Cutaneous), Large Cell Undifferentiated Malignant Neoplams

CPT Code(s): 88342 or 88341

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

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