Alpha-fetoprotein pin

IHC

Alpha-fetoprotein

Alternate Test Names:
AFP

Methodology: IHC

Clinical Significance:
Identifies yolk sac tumors that can be employed as part of a panel of markers of germ cell tumors. Not recommended in this setting as there are more sensitive and specific markers (e.g., glypican-3).

Subcellular Localization: Cytoplasm

Organ: Genitourinary, Liver, OB/GYN

Disease State:

CPT Code(s): 88342 or 88341

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

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