APL (Acute Promyelocytic Leukemia) Panel pin


Panel Components:
t(15;17) PML/RARA FISH
RARA (17q21) brreakapart
* Panel makeup subject to change

Methodology: FISH

Clinical Significance:
This panel detects the more commonly seen t(15;17) in acute promyelocytic leukemia (APL) as well as variant translocations detected by the RARA breakapart probe.

Organ: Blood/Bone Marrow, Body Fluids, Lymph Node / Spleen

Disease State: Acute Myeloid Leukemia (AML) / Myeloid Sarcoma

CPT Code(s): 88374x2 (reference only; CPTs may vary)

Turnaround Time: Within 3-4 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Peripheral blood, Preferred: 3 ml in sodium heparin (green top) / Acceptable: 3 ml in EDTA (purple top) - OR -
• Bone marrow aspirate, Preferred: 1-2 ml in sodium heparin (green top) / Acceptable: 1-2 ml in EDTA (purple top) - OR -
• Fresh tissue in RPMI

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