Alternate Test Names:
BCL2 (Clone C2)

Methodology: IHC

Clinical Significance:
C-2 is more sensitive than clone 124 in identifying bcl-2 protein expression in t(14;18)-positive follicular lymphomas. This increased sensitivity is possibly due to C-2 having been raised against a much larger portion of the bcl-2 protein than clone 124.

Subcellular Localization: Cytoplasmic

Organ:

Disease State: Follicular Lymphoma

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm