Methodology: IHC

Clinical Significance:
A nuclear protein expressed by normal germinal center B cells, by the large majority of follicular lymphomas, by a large subset of diffuse large B cell lymphomas, and by all Burkitt lymphomas. Bcl-6 is also expressed by the neoplastic “popcorn” or “L&H” cells of nodular lymphocyte predominant Hodgkin lymphoma. Subcellular Localization: Nuclear

Organ: Pancreas

Disease State: Angioimmunoblastic T Cell Lymphoma

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm