Methodology: IHC

Clinical Significance:
Identifies pCAM, a glycoprotein expressed in the vast majority of adenocarcinoma and almost always negative in mesothelioma (negative). Best used as part of a panel including antibodies to other glycoproteins such as the MOC-31 antibody to epithelial glycoprotein-2 and the Bg8-defined Lewis Y antigen. Subcellular Localization: Membranous and cytoplasmic

Organ: Lung

Disease State: Mesothelioma vs. Adenocarcinoma

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm