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IHC
Methodology: IHC
Clinical Significance:
Identifies pCAM, a glycoprotein expressed in the vast majority of adenocarcinoma and almost always negative in mesothelioma (negative). Best used as part of a panel including antibodies to other glycoproteins such as the MOC-31 antibody to epithelial glycoprotein-2 and the Bg8-defined Lewis Y antigen.
Subcellular Localization: Membranous and cytoplasmic
Organ: Lung
Disease State: Mesothelioma vs. Adenocarcinoma
CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm