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Calponin is a smooth muscle specific cytoskeletal protein useful in the identification of smooth muscle tumors and myoepithelium. Calponin is useful as a tool to demonstrate the presence of myoepithelium around suspicious cell nests and, as part of a panel, is helpful in distinguishing in situ vs. invasive lesions.
Subcellular Localization: Cytoplasmic
Disease State: Breast Cancer
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm