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Calponin pin



Methodology: IHC

Clinical Significance:
Calponin is a smooth muscle specific cytoskeletal protein useful in the identification of smooth muscle tumors and myoepithelium. Calponin is useful as a tool to demonstrate the presence of myoepithelium around suspicious cell nests and, as part of a panel, is helpful in distinguishing in situ vs. invasive lesions. Subcellular Localization: Cytoplasmic

Organ: Breast

Disease State: Breast Cancer

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm