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Calreticulin Exon 9 pin

PCR

Calreticulin Exon 9

Methodology: PCR

Clinical Significance:
Length-affecting mutations (insertions or deletions) within exon 9 of the Calreticulin (CALR) gene have been described in approximately 70% of essential thrombocythemia (ET) and approximately 60-80% of primary myelofibrosis (PMF) patients without JAK2 or MPL mutations. CALR exon 9 insertion/deletion mutations have not been identified in polycythemia vera (PV) patients.

Organ: Blood/Bone Marrow

Disease State: Myeloproliferative Neoplasms, Including Chronic Myelogenous Leukemia (CML)

CPT Code(s): 81219. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 4-8 business days of receipt

Schedule: Friday

Specimen Requirements:
Formalin-fixed, paraffin-embedded (FFPE) tissue block, 10 FFPE tissue slides, or peripheral blood or bone marrow in EDTA or heparin.