Alternate Test Names:
CA-IX; CAIX

Methodology: IHC

Clinical Significance:
Identifies renal cell carcinoma, as well as other clear cell carcinomas, e.g., from urothelium and adrenal cortex. May also provide prognostic information in CRCC, with low CA-IX expression correlating with poor survival.

Subcellular Localization: Cytoplasmic and membranous

Organ: Genitourinary

Disease State:

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm