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CD123 pin



Alternate Test Names:
Alternative test to TRAP

Methodology: IHC

Clinical Significance:
Identifies the interleukin-3 receptor. CD123 is strongly expressed in plasmacytoid dendritic cell neoplasms, at variable intensity in all classical hairy cell leukemia, most B-ALLs, and in a subset of AMLs.

Subcellular Localization: Membranous


Disease State: Blastic Plasmacytoid Dendritic Cell Neoplasm, Hairy Cell Leukemia

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

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