Methodology: IHC

Clinical Significance:
A cytoplasmic- and cell surface-associated protein that is strongly expressed by granulocytes at the promyelocyte and later stages, and is expressed at lower levels on monocytes/histiocytes. CD15 is aberrantly coexpressed by myeloid blasts in a subset of myeloid stem cell neoplasms. In addition, CD15 is expressed in a membrane and/or Golgi pattern in the majority of cases of classical Hodgkin lymphoma. Finally, CD15 is expressed by a subset of normal and neoplastic epithelia. Subcellular Localization: Membranous

Organ:

Disease State: Classical Hodgkin Lymphoma

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm