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CD30 (K-1 antigen) pin

IHC

CD30 (K-1 antigen)

Methodology: IHC

Clinical Significance:
CD30 is a cytoplasmic- and cell surface-associated protein expressed by a significant subset of activated B cells and T cells. CD30 is expressed at variable levels by Reed-Sternberg cells and variants in the majority of cases of classical Hodgkin lymphoma. Among the non-Hodgkin lymphomas, CD30 is strongly and uniformly expressed in anaplastic large cell lymphoma, and at variable levels in a significant subset of other non-Hodgkin lymphomas, particularly those of large cell type. CD30 is also expressed by embryonal carcinomas. Subcellular Localization: Membranous and cytoplasmic

Organ: OB/GYN

Disease State: Large Cell Undifferentiated Malignant Neoplams

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm