Methodology: IHC

Clinical Significance:
Identifies myeloid progenitors, monocytes, and macrophages. Acute and chronic myelogenous and monocytic leukemias, as well as acute lymphoblastic leukemias, express CD33. Some cases of multiple myeloma also express CD33.

Subcellular Localization: Membranous

Organ:

Disease State: Acute Myeloid Leukemia (AML) / Myeloid Sarcoma, Blastic Plasmacytoid Dendritic Cell Neoplasm, Plasma Cell Myeloma/Neoplasm

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm