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CD35 pin

IHC

CD35

Methodology: IHC

Clinical Significance:
CD35 is a follicular dendritic cell surface-associated protein. CD35 expression is present in a sharply defined FDC meshwork in many follicular lymphomas (e.g. centroblastic/centrocytic lymphoma) and a loose, ill-defined FDC meshwork of varying size in some diffuse lymphomas (most constantly in centrocytic lymphomas). A nodular form of lymphocyte-predominant type of Hodgkin disease (LPHD) is the only category of Hodgkin disease that has a characteristic meshwork of FDC. CD35 is also expressed on monocytes, neutrophils, and B cells. Subcellular Localization: Membranous

Organ:

Disease State: Nodular Lymphocyte-Predominant Hodgkin Lymphoma

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm