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CD42b pin

IHC

CD42b

Methodology: IHC

Clinical Significance:
CD42b, also known as platelet glycoprotein Ib, is a cell surface and transmembrane glycoprotein, expression of which commences somewhat later in megakaryocytic development compared to CD61. CD42b is also expressed by platelets.  A subset of cases of Bernard-Soulier syndrome involve congenital deficiency of CD42b. Subcellular Localization: Membranous

Organ:

Disease State:

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm