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CD43 pin



Methodology: IHC

Clinical Significance:
Identifies leukosialin, expressed on all leukocytes except resting B lymphocytes. Co-expression of CD43 with CD20 is a feature of a subset of low-grade lymphomas.

Subcellular Localization: Membranous


Disease State: Acute Myeloid Leukemia (AML) / Myeloid Sarcoma, Anaplastic Large Cell Lymphoma (Systemic or Cutaneous), Angioimmunoblastic T Cell Lymphoma, Blastic Plasmacytoid Dendritic Cell Neoplasm, Burkitt's Lymphoma, Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma (CLL/SLL), Langerhans Cell Histiocytosis, Large Cell Undifferentiated Malignant Neoplams, Lymphoplasmacytic Lymphoma, Mantle Cell Lymphoma, Marginal Zone/MALT Lymphoma, NK/T Cell Lymphoma, Nasal Type, Peripheral T Cell Lymphoma, NOS (of Large Cell Type), Small, Blue, Round Cell Tumors

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

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