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CD5-positive B cell therapy add-on tube pin

Flow Cytometry

CD5-positive B cell therapy add-on tube

Methodology: Flow Cytometry

Clinical Significance:
This tube assesses CD52 and CD22 on CD5+ B cell neoplasms (i.e., CLL/SLL and MCL). In addition to these two antibodies, this tube includes antibodies to CD45, CD19, CD5, CD49d, and CD79b; the latter two antibodies can aid in the distinction of CLL/SLL from MCL.

Organ: Blood/Bone Marrow

Disease State: Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma (CLL/SLL)

CPT Code(s): 88185x7 (reference only; CPTs may vary)

Turnaround Time: Physician will be contacted by 9:00 PM PST the day of receipt for acute/life threatening conditions; next business day for routine flow cases.

Schedule: Monday-Saturday

Specimen Requirements:
• Peripheral blood, Preferred: 3 ml in sodium heparin (green top) / Acceptable: 3 ml in EDTA (purple top) - OR - • Bone marrow aspirate, Preferred: 1-2 ml in sodium heparin (green top) / Acceptable: 1-2 ml in EDTA (purple top) - OR - • Tissue: Finely minced tissue in RPMI transport media - OR - • Body fluids: In RPMI transport media