Methodology: IHC

Clinical Significance:
CD57 is a cell surface-associated protein expressed on a subset of activated T cells, including so-called large granular lymphocytes, and neoplasms derived from these cells. CD57 is also expressed on a variety of neural structures. Identification of CD57-positive cells is of value in positively identifying lymphocyte-predominant Hodgkin lymphoma. Subcellular Localization: Membranous

Organ:

Disease State: Spindle Cell Tumors / Sarcoma Subtyping

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm