Methodology: IHC

Clinical Significance:
Identifies transferrin receptor (CD71), required for delivery of iron from transferrin to cells. In clinical practice, CD71 displays specificity for erythrocyte precursors in normal and abnormal bone marrow sections.

Subcellular Localization: Strong membranous staining with weak cytoplasmic staining in some cases

Organ: Blood/Bone Marrow

Disease State:

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm