CD7 is a cell surface-associated protein expressed in both mature and immature T cells, as well as NK cells. CD7 is aberrantly decreased in a subset of T cell and natural killer cell neoplasms. In addition, a significant subset of myeloid stem cell neoplasms, including acute myeloid leukemia and myelodysplastic or myeloproliferative syndromes, demonstrates aberrant coexpression of CD7 on the myeloid blasts.
Subcellular Localization: Membranous
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm