Methodology: IHC

Clinical Significance:
CD79a is a cytoplasmic antigen expressed at all stages of B cell maturation, from lymphoblasts through plasma cells. CD79a expression is decreased in most cases of classical Hodgkin lymphoma, and in a subset of non-Hodgkin B cell lymphomas.

Subcellular Localization: Membranous

Organ:

Disease State: B Cell Non-Hodgkin Lymphoma (not otherwise classified), Classical Hodgkin Lymphoma, Nodular Lymphocyte-Predominant Hodgkin Lymphoma

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm