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CDX2 pin



Methodology: IHC

Clinical Significance:
CDX2 is an intestinal-specific transcription factor, highly expressed in colorectal adenocarcinomas, with a sensitivity > 95%, and also expressed, at lower levels, and with a lower sensitivty, in the vast majority of non-colorectal GI carcinomas, i.e., those primary to the pancreatobiliary tract and stomach. CDX2 is also expressed in neuroendocrine carcinomas of the GI tract. Subcellular Localization: Nuclear

Organ: Liver

Disease State: Carcinomas of Unknown Primary

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm