Methodology: Flow Cytometry

Clinical Significance:
In combination with CD5+ B cell therapy tube, this tube helps distinguish CLL/SLL from mantle cell lymphoma. This tube includes antibodies to CD45, FMC7, CD19, CD22, CD5, CD23, CD200, and CD43.

Organ: Blood/Bone Marrow

Disease State: Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma (CLL/SLL)

CPT Code(s): 88185x10 (reference only; CPTs may vary)

Turnaround Time: Physician will be contacted by 9:00 PM PST the day of receipt for acute/life threatening conditions; next business day for routine flow cases.

Schedule: Monday-Saturday

Specimen Requirements:
• Peripheral blood, Preferred: 3 ml in sodium heparin (green top) / Acceptable: 3 ml in EDTA (purple top) - OR - • Bone marrow aspirate, Preferred: 1-2 ml in sodium heparin (green top) / Acceptable: 1-2 ml in EDTA (purple top) - OR - • Tissue: Finely minced tissue in RPMI transport media - OR - • Body fluids: In RPMI transport media