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Clusterin pin

IHC

Clusterin

Methodology: IHC

Clinical Significance:
Identifies a heterodimeric protein associated with clearance of cell debris and apoptosis. It is expressed in diffuse large B-cell lymphomas (DLBCL), T-cell rich large B-cell lymphoma, Hodgkin lymphoma, as well as various carcinomas. Clusterin has proven to be an effective tool in the differentiation of anaplastic large cell lymphoma (ALCL) from peripheral T cell lymphoma (PTCL), NOS. Subcellular Localization: Cytoplasmic, in a granular diffuse and/or a Golgi pattern

Organ:

Disease State: Anaplastic Large Cell Lymphoma (Systemic or Cutaneous)

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm