Cyclin D1 pin


Cyclin D1

Alternate Test Names:
Alternative test to TRAP

Methodology: IHC

Clinical Significance:
Identifies cyclin D1, one of the more frequently altered cell cycle regulators in cancers. Uniform overexpression of Cyclin D1, can be helpful in the identification of mantle cell lymphomas.

Subcellular Localization: Nuclear


Disease State: Hairy Cell Leukemia, Mantle Cell Lymphoma, Plasma Cell Myeloma/Neoplasm

CPT Code(s): 88342 or 88341

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

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