Methodology: IHC

Clinical Significance:
Desmin is an intermediate filament protein, expression of which is largely restricted to skeletal, smooth and cardiac muscle cells and tumors (e.g., leiomyosarcoma, rhabdomyosarcoma). Also expressed in reactive mesothelium and angiomatoid fibrous histiocytoma. Subcellular Localization: Cytoplasmic

Organ: Skin & Mucosa

Disease State: Small, Blue, Round Cell Tumors

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm