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Desmin is an intermediate filament protein, expression of which is largely restricted to skeletal, smooth and cardiac muscle cells and tumors (e.g., leiomyosarcoma, rhabdomyosarcoma). Also expressed in reactive mesothelium and angiomatoid fibrous histiocytoma.
Subcellular Localization: Cytoplasmic
Organ: Skin & Mucosa
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm