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Methodology: IHC

Clinical Significance:
Identifies EBV LMP-1 (latent membrane protein-1). EBV-LMP is a cell surface-associated protein encoded by the EBV genome and expressed by a subset of EBV-infected B cells, more commonly in tonsils than in lymph nodes of EBV-infected individuals. LMP-1 is a much less sensitive marker of EBV infection than EBER1 mRNA; the latter is detected by in situ hybridization. Subcellular Localization: Membranous


Disease State: Identification of Organisms

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm