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FOXP1 pin



Methodology: IHC

Clinical Significance:
Identifies: A non-lineage-specific nuclear transcription factor expressed in normal mature B cells at several stages of development, and in a variety of non-Hodgkin lymphomas, but not in Hodgkin lymphomas.  FOXP1 is used as part of a panel of markers in immunohistochemical distinction of germinal center-derived diffuse large B cell lymphoma (DLBCL) from non-germinal center-derived DLBCL. Subcellular Localization: Nuclear

Organ: Genitourinary Tumors

Disease State: Diffuse Large B Cell Lymphoma

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm