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Galectin-3 pin



Methodology: IHC

Clinical Significance:
Identifies: Galectin-3, a member of the lectin family, is upregulated in thyroid carcinoma, and can be employed as part of a panel of markers to assist in the distinction of thyroid carcinomas from adenomas. In the latter setting, galectin-3 has been demonstrated to be strongly and diffusely positive in papillary thyroid carcinomas, but weakly and focally positive in adenomas. Subcellular Localization: Nuclear and cytoplasmic

Organ: Thyroid

Disease State:

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm