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GATA-3 pin



Methodology: IHC

Clinical Significance:
GATA-3 is a zinc finger nuclear transcription factor that is a highly sensitive marker of carcinomas primary to the bladder and breast. GATA-3 is also expressed in a subset of squamous cell carcinomas, skin adnexal tumors, mesotheliomas, and salivary gland tumors, among others (Miettinen M et al. AJSP 38:13-22, 2014).

Organ: Breast

Disease State: Carcinomas of Unknown Primary

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm