Hairy Cell Leukemia (DBA.44) pin

IHC

Hairy Cell Leukemia (DBA.44)

Alternate Test Names:
DBA44

Methodology: IHC

Clinical Significance:
Identifies: An uncharacterized antigen present in >97% of cases of hairy cell leukemia. Other tumors positive include a high fraction of cases of splenic lymphomas with villous lymphocytes, and a smaller fraction of high grade B cell lymphomas (e.g., immunoblastic). The antibody shows strong positive staining of about 35% of cases of high-grade B cell lymphomas, e.g. centroblastic and immunoblastic types.

Subcellular Localization: Cytoplasmic

Organ:

Disease State: Hairy Cell Leukemia

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

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