Methodology: Flow Cytometry

Clinical Significance:
This tube is particularly useful to look for hairy cell leukemia, and to distinguish this entity from marginal zone lymphoma and other lymphomas that can have some overlapping immunophenotypes. The tube contains antibodies to CD45, CD103, CD22, CD25, CD5, CD11c, CD19, and CD38.

Organ: Blood/Bone Marrow

Disease State: B Cell NHL with Plasmacytoid Differentiation

CPT Code(s): 88185x8 (reference only; CPTs may vary)

Turnaround Time: Physician will be contacted by 9:00 PM PST the day of receipt for acute/life threatening conditions; next business day for routine flow cases.

Schedule: Monday-Saturday

Specimen Requirements:
• Peripheral blood, Preferred: 3 ml in sodium heparin (green top) / Acceptable: 3 ml in EDTA (purple top) - OR - • Bone marrow aspirate, Preferred: 1-2 ml in sodium heparin (green top) / Acceptable: 1-2 ml in EDTA (purple top) - OR - • Tissue: Finely minced tissue in RPMI transport media - OR - • Body fluids: In RPMI transport media