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HBME-1 pin



Methodology: IHC

Clinical Significance:
Identifies: A protein originally described as a positive marker of mesotheliomas, but other markers are currently employed for that purpose (e.g., calretinin, WT-1, podoplanin, cytokeratin 5, etc.) HMBE-1, however, has been found to be useful as part of a panel of markers in the distinction of thyroid carcinomas from adenomas. Subcellular Localization: Membranous

Organ: Thyroid

Disease State:

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm