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HBME-1 pin



Methodology: IHC

Clinical Significance:
Identifies: A protein originally described as a positive marker of mesotheliomas, but other markers are currently employed for that purpose (e.g., calretinin, WT-1, podoplanin, cytokeratin 5, etc.) HMBE-1, however, has been found to be useful as part of a panel of markers in the distinction of thyroid carcinomas from adenomas. Subcellular Localization: Membranous

Organ: Thyroid

Disease State:

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm