IgD pin

IHC

IgD

Alternate Test Names:
Immunoglobulin D heavy chain

Methodology: IHC

Clinical Significance:
Identifies: IgD, or immunoglobulin D heavy chain, a cytoplasmic protein strongly expressed by naive/mantle zone B cells and a small subset of plasma cells, and weakly expressed by germinal center B cells. A subset of B cell non-Hodgkin lymphomas, generally of germinal center or pre-germinal center origin, express IgD.

Subcellular Localization: Membranous

Organ:

Disease State: Nodular Lymphocyte-Predominant Hodgkin Lymphoma

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

Tech Only