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Identifies: IgG localization by direct immunofluorescence is useful in the subclassification of bullous and other skin disorders, particularly when employed as part of a panel of FITC-conjugated antibodies, including those to C3, IgM and IgA. IgG deposits in the skin, with unique distributions, characterize a number of dermatologic disorders, including bullous pemphigoid, pemphigus, lupus, etc.
Subcellular Localization: Extracellular
Organ: Skin & Mucosa
CPT Code(s): 88346 or 88350 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
Skin biopsy in Michel's (aka Zeuss) fixative, with or without patient serum