Methodology: Immunofluorescence

Clinical Significance:
Identifies: IgM localization by direct immunofluorescence is useful in the subclassification of bullous and other skin disorders, particularly when employed as part of a panel of FITC-conjugated antibodies, including those to C3, IgG and IgA. IgM deposits in the skin, with unique patterns, are characteristic of specific dermatologic disorders, including vasculitis, lupus, and others. Subcellular Localization: Extracellular

Organ: Skin & Mucosa

Disease State:

CPT Code(s): 88346 or 88350 . The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
Skin biopsy in Michel's (aka Zeuss) fixative, with or without patient serum