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INPP4B pin

IHC

INPP4B

Methodology: IHC

Clinical Significance:
INPP4B encodes the inositol polyphosphate 4-phosatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This antibody is useful as a diagnostic aid for basal like breast carcinomas, as the absence of expression of INPP4B, has been shown in our hands to have a 90% sensitivity and 80% specificity for basal-like breast carcinomas, which closely reflects the reported literature. INPP4B will be run in a panel with other antibodies used in the diagnosis of basal-like breast carcinomas, such as, Nestin, Keratin 5, and c-kit. Subcellular Localization: membranous and cytoplasmic

Organ: Breast

Disease State: Breast Cancer

CPT Code(s): 88360. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm