Alternate Test Names:
Cytokeratin 19; CK19

Methodology: IHC

Clinical Significance:
Identifies a subset of epithelia and carcinomas. Published studies suggest that CK19 expression, along with expression of galectin-3 and HBME-1, is useful in differentiating papillary carcinomas of the thyroid from benign thyroid lesions.

Subcellular Localization: Cytoplasmic

Organ: Thyroid

Disease State:

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm