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Keratin 8, low molecular weight (35ßH11) pin

IHC

Keratin 8, low molecular weight (35ßH11)

Methodology: IHC

Clinical Significance:
This antibody is positive in most carcinomas, other than those of squamous cell origin (positivity is seen in some squamous cell carcinomas). This marker is not recommended as a screen for epithelial differentiation, as a “pankeratin” antibody such as the AE1/AE3 cocktail or OSCAR clone, is more efficacious. 35ßH11 has the identical specificity to the CAM5.2 clone (cytokeratin 8, one of the ‘low MW cytokeratins’). Subcellular Localization: Cytoplasmic

Organ: OB/GYN

Disease State:

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm