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Keratin 8, low molecular weight (35ßH11) pin


Keratin 8, low molecular weight (35ßH11)

Methodology: IHC

Clinical Significance:
This antibody is positive in most carcinomas, other than those of squamous cell origin (positivity is seen in some squamous cell carcinomas). This marker is not recommended as a screen for epithelial differentiation, as a “pankeratin” antibody such as the AE1/AE3 cocktail or OSCAR clone, is more efficacious. 35ßH11 has the identical specificity to the CAM5.2 clone (cytokeratin 8, one of the ‘low MW cytokeratins’). Subcellular Localization: Cytoplasmic

Organ: OB/GYN

Disease State:

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm