Keratins, high molecular weight (34ßE12) pin


Keratins, high molecular weight (34ßE12)

Alternate Test Names:
Cytokeratins, high molecular weight (34ßE12); 34BE12

Methodology: IHC

Clinical Significance:
Identifies "high molecular weight" cytokeratins. It is an excellent marker of squamous differentiation, as well as a marker of the outer cell layer in prostatic glands, which is absent in carcinoma.

Subcellular Localization: Cytoplasmic

Organ: Genitourinary, Prostate

Disease State:

CPT Code(s): 88342 or 88341

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

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