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LMO2 pin



Methodology: IHC

Clinical Significance:
Identifies: A cysteine-rich protein that also plays a central and crucial role in hematopoietic development. In the setting of diffuse large B-cell lymphomas (DLBCLs), LMO2 has high sensitivity in differentiating between germinal center B-cell (GCB) DLBCLs and non-GCB DLBCLs. Based on the recently published Tally Method algorithm, LMO2 will be used in a panel, along with CD10, GCET1, MUM1, and FoxP1, to help distinguish between GCB versus non-GCB origin among DLBCLs. Subcellular Localization: Nuclear


Disease State: Diffuse Large B Cell Lymphoma

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm