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Identifies: A cysteine-rich protein that also plays a central and crucial role in hematopoietic development. In the setting of diffuse large B-cell lymphomas (DLBCLs), LMO2 has high sensitivity in differentiating between germinal center B-cell (GCB) DLBCLs and non-GCB DLBCLs. Based on the recently published Tally Method algorithm, LMO2 will be used in a panel, along with CD10, GCET1, MUM1, and FoxP1, to help distinguish between GCB versus non-GCB origin among DLBCLs.
Subcellular Localization: Nuclear
Disease State: Diffuse Large B Cell Lymphoma
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm