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MALT Panel pin

FISH

Methodology: FISH

Clinical Significance:
This sensitive breakapart FISH assay detects any MALT gene rearrangement including the t(11;18) and the t(14;18). MALT1 gene rearrangements occur in a subset of extra-nodal marginal zone B cell lymphomas (MZBCL) and can aid in this diagnosis.

Organ: Blood/Bone Marrow

Disease State: B Cell Non-Hodgkin Lymphoma (not otherwise classified)

CPT Code(s): 88374 (reference only; CPTs may vary)

Turnaround Time: Within 4-6 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded tissue block or cell block - OR - • Minimum of 5 unstained slide cut at 4µm for each test requested