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The MALT1 beakapart FISH assay is a sensitive test that detects gene rearrangements involving the MALT1 gene but does distinguish between the different MALT1 translocation partners that have been described. The main MALT1 translocations that occur in human MALT lymphomas include the t(11;18)(q21;q21)/API-2-MALT and t(14;18)(q32;q21)/IgH-MALT. Identification of a MALT1 rearrangement is of diagnostic use in atypical B cell proliferations when the diagnosis of MALT lymphoma is being considered. Probe type: Dual color breakapart
Organ: Skin & Mucosa
Disease State: B Cell NHL with Plasmacytoid Differentiation
CPT Code(s): 88374 (reference only; CPTs may vary)
Turnaround Time: Within 4-6 business days of receipt
Schedule: Monday - Friday
• Formalin-fixed, paraffin-embedded tissue block or cell block - OR - • Minimum of 5 unstained slide cut at 4µm for each test requested