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FISH
Methodology: FISH
Clinical Significance:
In this reflexive panel a MALT1 breakapart FISH assay is performed. If negative, no more testing is performed. If positive, one additional FISH assay is performed to positively identify and confirm the presence of t(11;18), which is the most common MALT1 gene translocation that occurs in MZBCL.
Organ: Blood/Bone Marrow
Disease State: B Cell Non-Hodgkin Lymphoma (not otherwise classified)
CPT Code(s): 88374x2 (reference only; CPTs may vary)
Turnaround Time: Within 4-6 business days of receipt
Schedule: Monday - Friday
Specimen Requirements:
• Formalin-fixed, paraffin-embedded tissue block or cell block - OR -
• Minimum of 5 unstained slide cut at 4µm for each test requested