Methodology: IHC

Clinical Significance:
Identifies: Mesothelin, a cell surface protein expressed by mesothelial cells and mesothelioma, but also by ovarian carcinoma and pancreatic adenocarcinoma. Displays significantly less specificity for mesotheliomas than other markers such as WT-1, calretinin, and podoplanin. Subcellular Localization: Membranous

Organ: Lung

Disease State: Mesothelioma vs. Adenocarcinoma

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm