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IHC
Methodology: IHC
Clinical Significance:
Identifies: Epithelial glycoprotein 2, a cell surface protein, expression of which has been demonstrated to help in the distinction of adenocarcinoma (positive) from mesothelioma (negative). As mesotheliomas can express low levels of this protein, this marker is best employed as part of a panel of markers.
Subcellular Localization: Membranous
Organ: Lung
Disease State: Mesothelioma vs. Adenocarcinoma
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm