Muscle actins (HHF35) pin

IHC

Muscle actins (HHF35)

Alternate Test Names:
Actin, muscle specific
HHF35

Methodology: IHC

Clinical Significance:
Identifies smooth, skeletal, and cardiac isoforms of actin. HHF35 can be employed as a marker of leiomyosarcomas, rhabdomyosarcomas, and tumors showing myoepithelial differentiation.

Subcellular Localization: Cytoplasmic

Organ:

Disease State: Spindle Cell Tumors / Sarcoma Subtyping

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

Tech Only