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Antibodies to myoglobin can be employed to identify myoglobin-containing casts within renal tubules, which can be seen following rhabdomyolysis and in cases of myoglobin cast nephropathy. Myoglobin is NOT recommended as a marker of rhabdomyosarcoma, as much more sensitive markers such as myogenin, myoD1, and desmin are best employed in this setting. Clinical Indication(s): This anti-myoglobin antibody will be used to identify the presence of myoglobin-containing tubular casts in the lumina of renal tubules. Subcellular Localization: Cytoplasmic
Disease State: Renal disease
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm