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NapsinA pin



Methodology: IHC

Clinical Significance:
Identifies: An aspartic protease expressed at high levels by type II pneumocytes of the lung. NapsinA is a highly sensitive and specific marker of pulmonary adenocarcinoma, although it can also be expressed in a subset of renal cell carcinomas and ovarian carcinomas (i.e., clear cell carcinomas). Subcellular Localization: Granular cytoplasmic

Organ: Lung

Disease State: Carcinomas of Unknown Primary

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm